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Holdings, Q2 2026

Largest first. Common shares only.

Latest 13F holdings
#The fund's own figures at the end of the quarter. A report can be up to 45 days old when it is filed. Options and bonds are not counted here.Filing
1PRAX
Praxis Precision Medicines, Inc.
640,000$214.3M11.0%-27.7%13F ↗
2BBOT
BridgeBio Oncology Therapeutics, Inc.
17.88M$136.2M7.0%Unchanged13F ↗
3PBLS
Parabilis Medicines, Inc.
4.62M$126.3M6.5%New13F ↗
4RAPP
Rapport Therapeutics, Inc.
2.66M$110.7M5.7%-10.1%13F ↗
5ERAS
Erasca, Inc.
6.00M$109.9M5.6%+3.4%13F ↗
6EWTX
Edgewise Therapeutics, Inc.
2.51M$102.0M5.2%-23.0%13F ↗
7EYPT
EyePoint, Inc.
7.00M$100.1M5.1%-15.3%13F ↗
8ALMS
Alumis Inc.
3.29M$92.5M4.7%-16.8%13F ↗
9ABVX
Abivax SA · ADR
675,000$90.0M4.6%-11.2%13F ↗
10DNTH
Dianthus Therapeutics, Inc.
750,000$73.1M3.7%-21.1%13F ↗
11DRUG
Bright Minds Biosciences Inc.
900,000$63.2M3.2%-15.0%13F ↗
12MLTX
MoonLake Immunotherapeutics
3.21M$62.4M3.2%-28.5%13F ↗
13BIOA
BioAge Labs, Inc.
2.39M$58.6M3.0%-17.3%13F ↗
14ORKA
Oruka Therapeutics, Inc.
533,340$50.8M2.6%Unchanged13F ↗
15ANL
Adlai Nortye Group Ltd. · ADR
3.98M$45.7M2.3%+37.3%13F ↗
16BBIO
BridgeBio Pharma, Inc.
550,000$41.0M2.1%-35.3%13F ↗
17TNGX
Tango Therapeutics, Inc.
1.30M$40.6M2.1%-8.8%13F ↗
18BHVN
Biohaven Ltd.
2.61M$38.8M2.0%+48.3%13F ↗
19AGMB
AgomAb Therapeutics NV · ADR
2.47M$32.0M1.6%Unchanged13F ↗
20MBX
MBX Biosciences, Inc.
550,000$30.4M1.6%-50.9%13F ↗
21CLYM
Climb Bio, Inc.
2.11M$27.5M1.4%New13F ↗
22OLMA
Olema Oncology, Inc.
2.15M$26.9M1.4%-44.9%13F ↗
23Damora Therapeutics Inc1.00M$26.0M1.3%-34.4%13F ↗
24PHVS
Pharvaris N.V.
750,000$25.9M1.3%-25.0%13F ↗
25CRBP
Corbus Pharmaceuticals Holdings, Inc.
2.34M$22.0M1.1%Unchanged13F ↗
26SYRE
Spyre Therapeutics, Inc.
225,000$20.0M1.0%New13F ↗
27DFTX
Definium Therapeutics, Inc.
400,000$18.8M1.0%New13F ↗
28NAMS
NewAmsterdam Pharma Company N.V.
500,000$16.9M0.9%-47.4%13F ↗
29ROIV
Roivant Sciences Ltd.
475,000$16.8M0.9%-36.7%13F ↗
30CABA
Cabaletta Bio, Inc.
5.00M$15.6M0.8%-9.1%13F ↗
31HLXC
Helix Acquisition Corp. III
1.30M$13.8M0.7%Unchanged13F ↗
32ASND
Ascendis Pharma A/S
50,000$13.3M0.7%New13F ↗
33KLRA
Kailera Therapeutics, Inc.
550,000$12.1M0.6%New13F ↗
34INSM
Insmed Incorporated · Com Par $.01
75,000$8.0M0.4%-60.5%13F ↗
35FTH
Faeth Therapeutics, Inc.
1.03M$7.7M0.4%+236%13F ↗
36ELVN
Enliven Therapeutics, Inc.
150,000$7.6M0.4%New13F ↗
37TARS
Tarsus Pharmaceuticals, Inc.
100,000$6.3M0.3%-55.6%13F ↗
38IBIO
iBio, Inc.
3.57M$6.2M0.3%New13F ↗
39Crinetics Pharmaceuticals In125,000$4.7M0.2%-50.0%13F ↗
40ARQT
Arcutis Biotherapeutics, Inc.
175,000$4.6M0.2%-61.1%13F ↗
41ARWR
Arrowhead Pharmaceuticals, Inc.
50,000$4.1M0.2%-50.0%13F ↗
42GPCR
Structure Therapeutics Inc.
75,000$4.0M0.2%-57.1%13F ↗
43RACC
Research Alliance Corporation III
370,000$4.0M0.2%New13F ↗
44COGT
Cogent Biosciences, Inc.
100,000$3.9M0.2%-50.0%13F ↗
45ALT
Altimmune, Inc.
1.25M$3.8M0.2%New13F ↗
46AMLX
Amylyx Pharmaceuticals, Inc.
200,000$3.6M0.2%-42.9%13F ↗
47ODTX
Odyssey Therapeutics, Inc.
175,000$3.3M0.2%New13F ↗
48PCVX
Vaxcyte, Inc.
50,000$2.9M0.1%-50.0%13F ↗
49BOLD
Boundless Bio, Inc.
1.00M$2.5M0.1%New13F ↗
50IRLA
IRulya Therapeutics Inc.
5,498$100.0K<0.1%New13F ↗

Changes since Q1 2026

13 new, 4 added to, 28 trimmed, 9 exited, 5 unchanged. By estimated dollars.

New positions (13)

New positions
PBLS
Parabilis Medicines, Inc.
4.62MNew$126.3M
CLYM
Climb Bio, Inc.
2.11MNew$27.5M
SYRE
Spyre Therapeutics, Inc.
225,000New$20.0M
DFTX
Definium Therapeutics, Inc.
400,000New$18.8M
ASND
Ascendis Pharma A/S
50,000New$13.3M
KLRA
Kailera Therapeutics, Inc.
550,000New$12.1M
ELVN
Enliven Therapeutics, Inc.
150,000New$7.6M
IBIO
iBio, Inc.
3.57MNew$6.2M
RACC
Research Alliance Corporation III
370,000New$4.0M
ALT
Altimmune, Inc.
1.25MNew$3.8M

Added to (4)

Added to
BHVN
Biohaven Ltd.
2.61M+48.3%$12.6M
ANL
Adlai Nortye Group Ltd. · ADR
3.98M+37.3%$12.4M
FTH
Faeth Therapeutics, Inc.
1.03M+236%$5.4M
ERAS
Erasca, Inc.
6.00M+3.4%$3.7M

Trimmed (28)

Trimmed
PRAX
Praxis Precision Medicines, Inc.
640,000-27.7%-$82.2M
MBX
MBX Biosciences, Inc.
550,000-50.9%-$31.5M
EWTX
Edgewise Therapeutics, Inc.
2.51M-23.0%-$30.5M
MLTX
MoonLake Immunotherapeutics
3.21M-28.5%-$24.8M
BBIO
BridgeBio Pharma, Inc.
550,000-35.3%-$22.3M
OLMA
Olema Oncology, Inc.
2.15M-44.9%-$21.9M
DNTH
Dianthus Therapeutics, Inc.
750,000-21.1%-$19.5M
ALMS
Alumis Inc.
3.29M-16.8%-$18.7M
EYPT
EyePoint, Inc.
7.00M-15.3%-$18.1M
NAMS
NewAmsterdam Pharma Company N.V.
500,000-47.4%-$15.3M

Exited (9)

Exited
Centessa Pharmaceuticals plc
ADR
1.05MExited-$41.7M
MAZE
Maze Therapeutics, Inc.
750,000Exited-$22.4M
Ascendis Pharma A/S
ADR
95,000Exited-$21.7M
Terns Pharmaceuticals Inc300,000Exited-$15.8M
ZURA
Zura Bio Limited
1.45MExited-$8.6M
AXSM
Axsome Therapeutics, Inc.
50,000Exited-$8.5M
GLUE
Monte Rosa Therapeutics, Inc.
400,000Exited-$6.6M
RLYB
Rallybio Corporation
400,000Exited-$3.6M
CNTX
Context Therapeutics Inc.
529,550Exited-$1.4M

The 10 largest of each, by estimated dollars: shares changed times the later report's price. Index tracking, splits and mergers move positions too.

Compare two quarters

Pick any two quarters: what is new, added to, trimmed or exited. Premium plan.

Reported value by quarter

Value and number of positions at the end of each quarter.

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Largest positions in earlier quarters

Pick a quarter to see what the fund's biggest positions were then.

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Ten largest positions

By value, Q2 2026.

$0$100.0M$200.0M$300.0MPRAX · Value: $214,265,600PRAXBBOT · Value: $136,234,886BBOTPBLS · Value: $126,329,300PBLSRAPP · Value: $110,738,900RAPPERAS · Value: $109,920,000ERASEWTX · Value: $101,981,300EWTXEYPT · Value: $100,100,000EYPTALMS · Value: $92,456,671ALMSABVX · Value: $89,950,500ABVXDNTH · Value: $73,110,000DNTH

Filings

13F filings
Filing
Q2 2026Aug 14, 202613F-HR50$2.0BCurrentSEC ↗
Q1 2026May 15, 202613F-HR47$2.0BCurrentSEC ↗
Q4 2025Feb 17, 202613F-HR35$2.2BCurrentSEC ↗
Q3 2025Nov 14, 202513F-HR36$1.4BCurrentSEC ↗
Q2 2025Aug 14, 202513F-HR42$1.3BCurrentSEC ↗
Q1 2025May 15, 202513F-HR44$1.3BCurrentSEC ↗

Most recent first, up to 80. An amendment can replace a report or add holdings to it. All 13F filings

Information, not investment advice. Values are the fund's own figures at quarter end; a report can be up to 45 days old when filed. Disclaimer