Funds › ADAR1 Capital Management, LLC
ADAR1 Capital Management, LLC
13F for Q2 2026, filed Aug 14, 2026. 262 positions worth $2.2B.Managers with more than $100 million in US-listed stocks list their holdings each quarter, within 45 days of quarter end. Long positions only: no short sales or cash.
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Holdings, Q2 2026
Largest first. Common shares only; puts and calls are under All positions.
| # | The fund's own figures at the end of the quarter. A report can be up to 45 days old when it is filed. Options and bonds are not counted here. | Filing | ||||
|---|---|---|---|---|---|---|
| 1 | ABVX Abivax SA · ADR | 1.80M | $240.5M | 11.0% | +29.5% | 13F ↗ |
| 2 | PTGX Protagonist Therapeutics, Inc. | 960,863 | $117.8M | 5.4% | -3.3% | 13F ↗ |
| 3 | ROIV Roivant Sciences Ltd. | 3.16M | $111.7M | 5.1% | -3.9% | 13F ↗ |
| 4 | SPY State Street SPDR S&P 500 ETF Trust · Trust units | 129,087 | $96.4M | 4.4% | +70.0% | 13F ↗ |
| 5 | IMVT Immunovant, Inc. | 2.33M | $89.8M | 4.1% | -13.0% | 13F ↗ |
| 6 | ZLAB Zai Lab Limited · ADR | 3.37M | $64.0M | 2.9% | +136% | 13F ↗ |
| 7 | AGIO Agios Pharmaceuticals, Inc. | 1.29M | $47.8M | 2.2% | +816% | 13F ↗ |
| 8 | Crinetics Pharmaceuticals In | 1.22M | $45.7M | 2.1% | +7.3% | 13F ↗ |
| 9 | Ea Series Trust Alpha Arch 1-3 | 337,125 | $39.5M | 1.8% | Unchanged | 13F ↗ |
| 10 | CYTK Cytokinetics, Incorporated | 457,907 | $39.0M | 1.8% | -27.6% | 13F ↗ |
| 11 | SEPN Septerna, Inc. | 940,747 | $31.5M | 1.4% | -13.7% | 13F ↗ |
| 12 | AVR Anteris Technologies Global Corp. | 3.15M | $31.0M | 1.4% | -17.0% | 13F ↗ |
| 13 | EDIT Editas Medicine, Inc. | 8.89M | $28.8M | 1.3% | New | 13F ↗ |
| 14 | DNLI Denali Therapeutics Inc. | 1.03M | $26.5M | 1.2% | -45.0% | 13F ↗ |
| 15 | SYRE Spyre Therapeutics, Inc. | 283,982 | $25.2M | 1.2% | -16.1% | 13F ↗ |
| 16 | VIR Vir Biotechnology, Inc. | 2.46M | $25.0M | 1.1% | -10.5% | 13F ↗ |
| 17 | PRAX Praxis Precision Medicines, Inc. | 74,253 | $24.9M | 1.1% | +4850% | 13F ↗ |
| 18 | INSM Insmed Incorporated · Com Par $.01 | 228,520 | $24.4M | 1.1% | +546% | 13F ↗ |
| 19 | CLDX Celldex Therapeutics, Inc. | 619,542 | $23.1M | 1.1% | +44.8% | 13F ↗ |
| 20 | VKTX Viking Therapeutics, Inc. | 574,038 | $22.4M | 1.0% | +152% | 13F ↗ |
| 21 | TSHA Taysha Gene Therapies, Inc. | 3.04M | $20.7M | 0.9% | +2.0% | 13F ↗ |
| 22 | MNPR Monopar Therapeutics Inc. | 217,595 | $20.1M | 0.9% | -17.7% | 13F ↗ |
| 23 | OVID Ovid Therapeutics Inc. | 7.42M | $20.0M | 0.9% | +63.2% | 13F ↗ |
| 24 | ELVN Enliven Therapeutics, Inc. | 387,718 | $19.7M | 0.9% | +17.7% | 13F ↗ |
| 25 | ENTA Enanta Pharmaceuticals, Inc. | 1.34M | $19.6M | 0.9% | +2518% | 13F ↗ |
| 26 | NKTR Nektar Therapeutics | 244,184 | $17.0M | 0.8% | +51.4% | 13F ↗ |
| 27 | INSP Inspire Medical Systems, Inc. | 374,617 | $16.7M | 0.8% | -7.5% | 13F ↗ |
| 28 | RVMD Revolution Medicines, Inc. | 87,509 | $16.4M | 0.7% | -34.6% | 13F ↗ |
| 29 | ESTA Establishment Labs Holdings Inc. | 185,619 | $15.9M | 0.7% | -13.0% | 13F ↗ |
| 30 | PRTA Prothena Corporation plc | 1.55M | $15.2M | 0.7% | -1.7% | 13F ↗ |
| 31 | RYTM Rhythm Pharmaceuticals, Inc. | 136,158 | $15.1M | 0.7% | -35.6% | 13F ↗ |
| 32 | IKT Inhibikase Therapeutics, Inc. | 7.39M | $15.0M | 0.7% | +11.8% | 13F ↗ |
| 33 | QURE uniQure N.V. | 324,672 | $15.0M | 0.7% | +326% | 13F ↗ |
| 34 | RLYB Rallybio Corporation | 926,352 | $14.8M | 0.7% | +4411% | 13F ↗ |
| 35 | REGN Regeneron Pharmaceuticals, Inc. | 22,208 | $13.8M | 0.6% | +82.7% | 13F ↗ |
| 36 | IVA Inventiva S.A. · ADR | 3.61M | $13.6M | 0.6% | +65.9% | 13F ↗ |
| 37 | STRO Sutro Biopharma, Inc. | 404,014 | $13.4M | 0.6% | -23.0% | 13F ↗ |
| 38 | IONS Ionis Pharmaceuticals, Inc. | 166,286 | $13.2M | 0.6% | +3.7% | 13F ↗ |
| 39 | BBIO BridgeBio Pharma, Inc. | 176,689 | $13.2M | 0.6% | +87.4% | 13F ↗ |
| 40 | SRPT Sarepta Therapeutics, Inc. | 730,649 | $13.1M | 0.6% | +179% | 13F ↗ |
| 41 | CTMX CytomX Therapeutics, Inc. | 3.37M | $12.6M | 0.6% | -1.3% | 13F ↗ |
| 42 | VOR Vor Biopharma Inc. | 680,626 | $12.5M | 0.6% | New | 13F ↗ |
| 43 | Spdr Series Trust St Str Blo 1 Etf | 135,585 | $12.4M | 0.6% | Unchanged | 13F ↗ |
| 44 | EQ Equillium, Inc. | 3.76M | $12.0M | 0.6% | +0.9% | 13F ↗ |
| 45 | ANL Adlai Nortye Group Ltd. · ADR | 1.02M | $11.7M | 0.5% | +763% | 13F ↗ |
| 46 | CLYM Climb Bio, Inc. | 822,649 | $10.7M | 0.5% | +37.6% | 13F ↗ |
| 47 | HLXC Helix Acquisition Corp. III | 1.00M | $10.6M | 0.5% | Unchanged | 13F ↗ |
| 48 | ZURA Zura Bio Limited | 1.76M | $10.4M | 0.5% | +179% | 13F ↗ |
| 49 | OKUR OnKure Therapeutics, Inc. | 2.24M | $10.2M | 0.5% | -8.1% | 13F ↗ |
| 50 | MAZE Maze Therapeutics, Inc. | 339,276 | $10.1M | 0.5% | +577% | 13F ↗ |
Changes since Q1 2026
43 new, 96 added to, 65 trimmed, 72 exited, 58 unchanged. By estimated dollars.
New positions (43)
| EDIT Editas Medicine, Inc. | 8.89M | New | $28.8M |
| VOR Vor Biopharma Inc. | 680,626 | New | $12.5M |
| FTH Faeth Therapeutics, Inc. | 361,010 | New | $9.0M |
| ASND Ascendis Pharma A/S | 28,604 | New | $7.6M |
| AMAN Amanat Acquisition Corp | 750,000 | New | $7.6M |
| RACC Research Alliance Corporation III | 650,000 | New | $7.0M |
| RLAY Relay Therapeutics, Inc. | 358,333 | New | $6.7M |
| Disciplined Growth Acquis Co Units | 500,000 | New | $5.0M |
| BOLD Boundless Bio, Inc. | 1.97M | New | $4.9M |
| AVLN Avalyn Pharma Inc. | 146,447 | New | $4.8M |
Added to (96)
| ABVX Abivax SA · ADR | 1.80M | +29.5% | $54.7M |
| AGIO Agios Pharmaceuticals, Inc. | 1.29M | +816% | $42.6M |
| SPY State Street SPDR S&P 500 ETF Trust · Trust units | 129,087 | +70.0% | $39.7M |
| ZLAB Zai Lab Limited · ADR | 3.37M | +136% | $36.9M |
| PRAX Praxis Precision Medicines, Inc. | 74,253 | +4850% | $24.4M |
| INSM Insmed Incorporated · Com Par $.01 | 228,520 | +546% | $20.6M |
| ENTA Enanta Pharmaceuticals, Inc. | 1.34M | +2518% | $18.9M |
| RLYB Rallybio Corporation | 926,352 | +4411% | $14.5M |
| VKTX Viking Therapeutics, Inc. | 574,038 | +152% | $13.5M |
| QURE uniQure N.V. | 324,672 | +326% | $11.4M |
Trimmed (65)
| DNLI Denali Therapeutics Inc. | 1.03M | -45.0% | -$21.7M |
| CYTK Cytokinetics, Incorporated | 457,907 | -27.6% | -$14.9M |
| IMVT Immunovant, Inc. | 2.33M | -13.0% | -$13.4M |
| MPLT MapLight Therapeutics, Inc. | 26,497 | -92.9% | -$12.5M |
| SNY Sanofi | 57,100 | -82.0% | -$11.1M |
| REPL Replimune Group, Inc. | 655,784 | -58.6% | -$10.3M |
| AMLX Amylyx Pharmaceuticals, Inc. | 494,378 | -50.6% | -$9.1M |
| ABUS Arbutus Biopharma Corporation | 1.27M | -59.5% | -$9.0M |
| RVMD Revolution Medicines, Inc. | 87,509 | -34.6% | -$8.7M |
| MLTX MoonLake Immunotherapeutics | 27,000 | -94.1% | -$8.4M |
Exited (72)
| Terns Pharmaceuticals Inc | 914,699 | Exited | -$48.2M |
| BEAM Beam Therapeutics Inc. | 1.45M | Exited | -$34.5M |
| SRRK Scholar Rock Holding Corporation | 407,273 | Exited | -$20.0M |
| VRTX Vertex Pharmaceuticals Incorporated | 15,075 | Exited | -$6.7M |
| VRDN Viridian Therapeutics, Inc. | 304,422 | Exited | -$6.0M |
| Ascendis Pharma A/S ADR | 25,014 | Exited | -$5.7M |
| LLY Eli Lilly and Company | 5,060 | Exited | -$4.7M |
| DNTH Dianthus Therapeutics, Inc. | 55,000 | Exited | -$4.6M |
| BLTE Belite Bio, Inc | 26,880 | Exited | -$4.3M |
| Arcellx Inc | 32,084 | Exited | -$3.7M |
The 10 largest of each, by estimated dollars: shares changed times the later report's price. Index tracking, splits and mergers move positions too.
All positions
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Reported value by quarter
Value and number of positions at the end of each quarter.
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Largest positions in earlier quarters
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Ten largest positions
By value, Q2 2026.
Filings
| Filing | ||||||
|---|---|---|---|---|---|---|
| Q2 2026 | Aug 14, 2026 | 13F-HR | 277 | $2.2B | Current | SEC ↗ |
| Q1 2026 | May 18, 2026 | 13F-HR | 310 | $1.7B | Current | SEC ↗ |
| Q4 2025 | Feb 18, 2026 | 13F-HR/A (restatement) | 270 | $1.4B | Current | SEC ↗ |
| Q4 2025 | Feb 17, 2026 | 13F-HR | 270 | $1.4B | Replaced | SEC ↗ |
| Q3 2025 | Nov 14, 2025 | 13F-HR | 217 | $1.1B | Current | SEC ↗ |
| Q2 2025 | Aug 14, 2025 | 13F-HR | 210 | $652.1M | Current | SEC ↗ |
| Q1 2025 | May 15, 2025 | 13F-HR | 202 | $538.7M | Current | SEC ↗ |
Most recent first, up to 80. An amendment can replace a report or add holdings to it. All 13F filings
Information, not investment advice. Values are the fund's own figures at quarter end; a report can be up to 45 days old when filed. Disclaimer