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Holdings, Q2 2026

Largest first. Common shares only.

Latest 13F holdings
#The fund's own figures at the end of the quarter. A report can be up to 45 days old when it is filed. Options and bonds are not counted here.Filing
1RVMD
Revolution Medicines, Inc.
2.97M$555.3M14.2%+3.8%13F ↗
2KYMR
Kymera Therapeutics, Inc.
3.87M$444.0M11.4%-29.6%13F ↗
3Xoma Royalty Corporation7.59M$322.7M8.3%+193%13F ↗
4MLTX
MoonLake Immunotherapeutics
16.00M$311.5M8.0%Unchanged13F ↗
5GHRS
GH Research PLC
8.65M$232.5M5.9%Unchanged13F ↗
6GPCR
Structure Therapeutics Inc.
3.37M$180.7M4.6%-2.7%13F ↗
7NKTR
Nektar Therapeutics
2.39M$166.9M4.3%-6.6%13F ↗
8MIRM
Mirum Pharmaceuticals, Inc.
1.06M$123.6M3.2%-33.4%13F ↗
9XNCR
Xencor, Inc.
7.13M$114.9M2.9%Unchanged13F ↗
10ALKS
Alkermes plc
2.15M$112.9M2.9%+7.7%13F ↗
11GLUE
Monte Rosa Therapeutics, Inc.
4.46M$108.0M2.8%Unchanged13F ↗
12CGEM
Cullinan Therapeutics, Inc.
5.75M$104.7M2.7%Unchanged13F ↗
13PVLA
Palvella Therapeutics, Inc.
672,789$102.8M2.6%-30.0%13F ↗
14ZYME
Zymeworks Inc.
3.65M$95.4M2.4%-2.3%13F ↗
15KURA
Kura Oncology, Inc.
8.45M$92.7M2.4%Unchanged13F ↗
16IRON
Disc Medicine, Inc.
1.15M$84.4M2.2%-9.3%13F ↗
17STOK
Stoke Therapeutics, Inc.
2.55M$83.4M2.1%Unchanged13F ↗
18OLMA
Olema Oncology, Inc.
5.30M$66.3M1.7%Unchanged13F ↗
19ANNX
Annexon, Inc.
8.70M$49.7M1.3%Unchanged13F ↗
20CBIO
Crescent Biopharma, Inc.
2.75M$49.5M1.3%Unchanged13F ↗
21ACIU
AC Immune SA
19.82M$47.2M1.2%Unchanged13F ↗
22TYRA
Tyra Biosciences, Inc.
1.48M$47.1M1.2%-25.3%13F ↗
23STRO
Sutro Biopharma, Inc.
1.25M$41.6M1.1%Unchanged13F ↗
24IMCR
Immunocore Holdings plc · ADR
1.29M$41.1M1.1%Unchanged13F ↗
25AVTX
Avalo Therapeutics, Inc.
2.08M$38.4M1.0%+27.1%13F ↗
26FDMT
4D Molecular Therapeutics, Inc.
2.88M$38.3M1.0%Unchanged13F ↗
27QTTB
Q32 Bio Inc.
2.35M$29.9M0.8%New13F ↗
28AVR
Anteris Technologies Global Corp.
3.00M$29.6M0.8%Unchanged13F ↗
29FHTX
Foghorn Therapeutics Inc.
5.84M$28.5M0.7%Unchanged13F ↗
30ABSI
Absci Corporation
2.36M$27.4M0.7%New13F ↗
31ELDN
Eledon Pharmaceuticals, Inc.
6.29M$24.8M0.6%Unchanged13F ↗
32IVVD
Invivyd, Inc.
28.16M$24.6M0.6%+44.3%13F ↗
33SGMT
Sagimet Biosciences Inc.
2.50M$19.3M0.5%New13F ↗
34OKUR
OnKure Therapeutics, Inc.
3.24M$14.8M0.4%+63.5%13F ↗
35IMUX
Immunic, Inc.
765,295$11.8M0.3%New13F ↗
36XFOR
X4 Pharmaceuticals, Inc.
2.23M$10.4M0.3%Unchanged13F ↗
37IMA
ImageneBio, Inc.
1.11M$6.5M0.2%Unchanged13F ↗
38TCRX
TScan Therapeutics, Inc.
5.56M$5.5M0.1%Unchanged13F ↗
39RACC
Research Alliance Corporation III
500,000$5.3M0.1%New13F ↗
40MOLN
Molecular Partners AG · ADR
1.35M$5.1M0.1%Unchanged13F ↗
41TENX
Tenax Therapeutics, Inc.
339,549$4.9M0.1%Unchanged13F ↗
42ENTX
Entera Bio Ltd.
2.42M$4.3M0.1%New13F ↗
43IVA
Inventiva S.A. · ADR
686,040$2.6M0.1%Unchanged13F ↗
44ENGNW
enGene Therapeutics Inc. · Spac Combination
945,402$274.1K<0.1%New13F ↗

Changes since Q1 2026

7 new, 6 added to, 8 trimmed, 4 exited, 23 unchanged. By estimated dollars.

New positions (7)

New positions
QTTB
Q32 Bio Inc.
2.35MNew$29.9M
ABSI
Absci Corporation
2.36MNew$27.4M
SGMT
Sagimet Biosciences Inc.
2.50MNew$19.3M
IMUX
Immunic, Inc.
765,295New$11.8M
RACC
Research Alliance Corporation III
500,000New$5.3M
ENTX
Entera Bio Ltd.
2.42MNew$4.3M
ENGNW
enGene Therapeutics Inc. · Spac Combination
945,402New$274.1K

Added to (6)

Added to
Xoma Royalty Corporation7.59M+193%$212.6M
RVMD
Revolution Medicines, Inc.
2.97M+3.8%$20.3M
AVTX
Avalo Therapeutics, Inc.
2.08M+27.1%$8.2M
ALKS
Alkermes plc
2.15M+7.7%$8.1M
IVVD
Invivyd, Inc.
28.16M+44.3%$7.5M
OKUR
OnKure Therapeutics, Inc.
3.24M+63.5%$5.7M

Trimmed (8)

Trimmed
KYMR
Kymera Therapeutics, Inc.
3.87M-29.6%-$187.0M
MIRM
Mirum Pharmaceuticals, Inc.
1.06M-33.4%-$61.9M
PVLA
Palvella Therapeutics, Inc.
672,789-30.0%-$44.0M
TYRA
Tyra Biosciences, Inc.
1.48M-25.3%-$16.0M
NKTR
Nektar Therapeutics
2.39M-6.6%-$11.8M
IRON
Disc Medicine, Inc.
1.15M-9.3%-$8.7M
GPCR
Structure Therapeutics Inc.
3.37M-2.7%-$5.0M
ZYME
Zymeworks Inc.
3.65M-2.3%-$2.2M

Exited (4)

Exited
CMPX
Compass Therapeutics, Inc.
7.76MExited-$41.1M
SEPN
Septerna, Inc.
1.35MExited-$32.5M
Immunic Inc7.65MExited-$8.5M
Engene Holdings Inc
W Exp 10/31/2028
945,402Exited-$2.5M

The 10 largest of each, by estimated dollars: shares changed times the later report's price. Index tracking, splits and mergers move positions too.

Compare two quarters

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Reported value by quarter

Value and number of positions at the end of each quarter.

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Largest positions in earlier quarters

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Ten largest positions

By value, Q2 2026.

$0$200.0M$400.0M$600.0MRVMD · Value: $555,315,165RVMDKYMR · Value: $444,008,203KYMRXoma… · Value: $322,715,378Xoma…MLTX · Value: $311,544,999MLTXGHRS · Value: $232,516,247GHRSGPCR · Value: $180,697,390GPCRNKTR · Value: $166,920,946NKTRMIRM · Value: $123,629,081MIRMXNCR · Value: $114,852,892XNCRALKS · Value: $112,895,716ALKS

Filings

13F filings
Filing
Q2 2026Aug 14, 202613F-HR44$3.9BCurrentSEC ↗
Q1 2026May 15, 202613F-HR41$3.1BCurrentSEC ↗
Q4 2025Feb 17, 202613F-HR41$3.0BCurrentSEC ↗
Q3 2025Nov 14, 202513F-HR46$2.5BCurrentSEC ↗
Q2 2025Aug 14, 202513F-HR44$2.8BCurrentSEC ↗
Q1 2025May 15, 202513F-HR51$2.5BCurrentSEC ↗

Most recent first, up to 80. An amendment can replace a report or add holdings to it. All 13F filings

Information, not investment advice. Values are the fund's own figures at quarter end; a report can be up to 45 days old when filed. Disclaimer