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Holdings, Q2 2026

Largest first. Common shares only.

Latest 13F holdings
#The fund's own figures at the end of the quarter. A report can be up to 45 days old when it is filed. Options and bonds are not counted here.Filing
1AVLN
Avalyn Pharma Inc.
1.68M$55.2M10.4%New13F ↗
2JNJ
Johnson & Johnson
138,946$35.3M6.6%New13F ↗
3GILD
Gilead Sciences, Inc.
269,309$34.0M6.4%+64.3%13F ↗
4BBIO
BridgeBio Pharma, Inc.
455,041$33.9M6.4%+5.3%13F ↗
5SNDX
Syndax Pharmaceuticals, Inc.
1.22M$26.6M5.0%+16.5%13F ↗
6DFTX
Definium Therapeutics, Inc.
562,672$26.5M5.0%-45.8%13F ↗
7BMY
Bristol-Myers Squibb Company
412,961$23.8M4.5%-1.8%13F ↗
8PBLS
Parabilis Medicines, Inc.
824,043$22.6M4.2%New13F ↗
9NTRA
Natera, Inc.
82,181$22.3M4.2%+15.9%13F ↗
10INCY
Incyte Corporation
191,627$21.7M4.1%+5.2%13F ↗
11SEPN
Septerna, Inc.
536,152$18.0M3.4%+82.1%13F ↗
12MLYS
Mineralys Therapeutics, Inc.
648,722$17.5M3.3%+47.8%13F ↗
13HTFL
Heartflow, Inc.
583,055$17.1M3.2%+44.5%13F ↗
14CRVS
Corvus Pharmaceuticals, Inc.
1.08M$16.1M3.0%+21.2%13F ↗
15GPCR
Structure Therapeutics Inc.
276,550$14.8M2.8%+8.3%13F ↗
16PTGX
Protagonist Therapeutics, Inc.
106,799$13.1M2.5%New13F ↗
17IRON
Disc Medicine, Inc.
159,384$11.7M2.2%+29.6%13F ↗
18EW
Edwards Lifesciences Corporation
124,778$11.3M2.1%-13.7%13F ↗
19AXSM
Axsome Therapeutics, Inc.
43,182$10.6M2.0%New13F ↗
20RARE
Ultragenyx Pharmaceutical Inc.
316,252$10.6M2.0%-62.8%13F ↗
21KLRA
Kailera Therapeutics, Inc.
468,750$10.3M1.9%New13F ↗
22KPTI
Karyopharm Therapeutics Inc.
940,855$9.2M1.7%+4.8%13F ↗
23ODTX
Odyssey Therapeutics, Inc.
457,839$8.6M1.6%New13F ↗
24ASND
Ascendis Pharma A/S
31,759$8.5M1.6%New13F ↗
25KARD
Kardigan, Inc.
312,500$7.5M1.4%New13F ↗
26ELDN
Eledon Pharmaceuticals, Inc.
1.70M$6.7M1.3%+3.4%13F ↗
27FDMT
4D Molecular Therapeutics, Inc.
471,254$6.3M1.2%New13F ↗
28MANE
Veradermics, Incorporated
45,856$5.6M1.1%-73.6%13F ↗
29DYN
Dyne Therapeutics, Inc.
244,929$5.4M1.0%-13.4%13F ↗
30Fractyl Health Inc6.17M$4.9M0.9%+12.3%13F ↗
31IMCR
Immunocore Holdings plc · ADR
148,045$4.7M0.9%+75.5%13F ↗
32DNTH
Dianthus Therapeutics, Inc.
32,941$3.2M0.6%-94.1%13F ↗
33BBOT
BridgeBio Oncology Therapeutics, Inc.
318,407$2.4M0.5%New13F ↗
34TARA
Protara Therapeutics, Inc.
520,148$2.0M0.4%-10.3%13F ↗
35HYPR
Hyperfine, Inc.
1.32M$1.8M0.3%Unchanged13F ↗
36Ataibeckley Inc196,858$1.0M0.2%Unchanged13F ↗
37MGX
Metagenomi Therapeutics, Inc.
528,993$629.5K0.1%Unchanged13F ↗
38OM
Outset Medical, Inc.
118,279$511.0K0.1%Unchanged13F ↗
39FTH
Faeth Therapeutics, Inc.
14,718$367.9K0.1%Unchanged13F ↗

Changes since Q1 2026

11 new, 15 added to, 8 trimmed, 13 exited, 5 unchanged. By estimated dollars.

New positions (11)

New positions
AVLN
Avalyn Pharma Inc.
1.68MNew$55.2M
JNJ
Johnson & Johnson
138,946New$35.3M
PBLS
Parabilis Medicines, Inc.
824,043New$22.6M
PTGX
Protagonist Therapeutics, Inc.
106,799New$13.1M
AXSM
Axsome Therapeutics, Inc.
43,182New$10.6M
KLRA
Kailera Therapeutics, Inc.
468,750New$10.3M
ODTX
Odyssey Therapeutics, Inc.
457,839New$8.6M
ASND
Ascendis Pharma A/S
31,759New$8.5M
KARD
Kardigan, Inc.
312,500New$7.5M
FDMT
4D Molecular Therapeutics, Inc.
471,254New$6.3M

Added to (15)

Added to
GILD
Gilead Sciences, Inc.
269,309+64.3%$13.3M
SEPN
Septerna, Inc.
536,152+82.1%$8.1M
MLYS
Mineralys Therapeutics, Inc.
648,722+47.8%$5.7M
HTFL
Heartflow, Inc.
583,055+44.5%$5.3M
SNDX
Syndax Pharmaceuticals, Inc.
1.22M+16.5%$3.8M
NTRA
Natera, Inc.
82,181+15.9%$3.1M
CRVS
Corvus Pharmaceuticals, Inc.
1.08M+21.2%$2.8M
IRON
Disc Medicine, Inc.
159,384+29.6%$2.7M
IMCR
Immunocore Holdings plc · ADR
148,045+75.5%$2.0M
BBIO
BridgeBio Pharma, Inc.
455,041+5.3%$1.7M

Trimmed (8)

Trimmed
DNTH
Dianthus Therapeutics, Inc.
32,941-94.1%-$51.4M
DFTX
Definium Therapeutics, Inc.
562,672-45.8%-$22.4M
RARE
Ultragenyx Pharmaceutical Inc.
316,252-62.8%-$17.8M
MANE
Veradermics, Incorporated
45,856-73.6%-$15.7M
EW
Edwards Lifesciences Corporation
124,778-13.7%-$1.8M
DYN
Dyne Therapeutics, Inc.
244,929-13.4%-$844.5K
BMY
Bristol-Myers Squibb Company
412,961-1.8%-$447.5K
TARA
Protara Therapeutics, Inc.
520,148-10.3%-$228.7K

Exited (13)

Exited
Ascendis Pharma A/S
ADR
129,111Exited-$29.5M
Terns Pharmaceuticals Inc409,031Exited-$21.6M
Soleno Therapeutics Inc577,808Exited-$19.3M
BSX
Boston Scientific Corporation
299,318Exited-$18.8M
CYTK
Cytokinetics, Incorporated
215,501Exited-$14.2M
ADPT
Adaptive Biotechnologies Corporation
722,784Exited-$10.0M
Kalvista Pharmaceuticals Inc426,551Exited-$8.6M
QURE
uniQure N.V.
491,116Exited-$8.0M
ABVX
Abivax SA · ADR
47,193Exited-$5.3M
SUPN
Supernus Pharmaceuticals
62,019Exited-$3.2M

The 10 largest of each, by estimated dollars: shares changed times the later report's price. Index tracking, splits and mergers move positions too.

Compare two quarters

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Reported value by quarter

Value and number of positions at the end of each quarter.

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Largest positions in earlier quarters

Pick a quarter to see what the fund's biggest positions were then.

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Ten largest positions

By value, Q2 2026.

$0$20.0M$40.0M$60.0MAVLN · Value: $55,168,324AVLNJNJ · Value: $35,288,116JNJGILD · Value: $34,024,499GILDBBIO · Value: $33,891,454BBIOSNDX · Value: $26,575,158SNDXDFTX · Value: $26,468,091DFTXBMY · Value: $23,794,813BMYPBLS · Value: $22,554,057PBLSNTRA · Value: $22,308,032NTRAINCY · Value: $21,722,837INCY

Filings

13F filings
Filing
Q2 2026Aug 14, 202613F-HR39$532.1MCurrentSEC ↗
Q1 2026May 15, 202613F-HR41$478.7MCurrentSEC ↗
Q4 2025Feb 17, 202613F-HR45$565.8MCurrentSEC ↗
Q3 2025Nov 14, 202513F-HR38$540.9MCurrentSEC ↗
Q2 2025Aug 14, 202513F-HR40$476.9MCurrentSEC ↗
Q1 2025May 15, 202513F-HR37$411.1MCurrentSEC ↗

Most recent first, up to 80. An amendment can replace a report or add holdings to it. All 13F filings

Information, not investment advice. Values are the fund's own figures at quarter end; a report can be up to 45 days old when filed. Disclaimer