NasdaqHealth CareSurgical & Medical Instruments & ApparatusNEW HOPE, PA

Orchestra BioMed Holdings, Inc. OBIO

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Estimated market cap $570.61M78.70M shares, shares as of Nov 9, 2026CIK 1814114

Insider trades, 12 mo

13 buys · 6 sells

$343.8K sold, open market

Congress trades, 24 mo

—

No disclosed trades

13F holders, Q3 2026

12.2% of shares · 22 added

13F holders

…

Lobbying, 12 mo

—

No lobbying filings

Federal contracts, 12 mo

—

None matched

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Latest 10-Q

Q3 2026

What changed in Orchestra BioMed Holdings, Inc.'s latest quarterly report, compared with the one before.

Filed Nov 10, 2026 · Quarter ended Sep 30, 2026

Compared with the 10-Q for the quarter ended Jun 30, 2026. Sections compared: management's discussion, risk factors, legal proceedings and controls and procedures.

Read the 10-Q on sec.gov ↗Filing index ↗

Latest 10-Q

What changed in Orchestra BioMed Holdings, Inc.'s latest quarterly report, compared with the one before.

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Insider trades

19 in 12 mo

Open-market trades from Form 4. 10b5-1 marks a plan set in advance.

Recent insider trades

RTW Investments, LP 10% owner	Nov 9 Form 4 ↗	Buy	+$6.0M 1.20M sh @ $5.00	+27.0%
Eric S. Fain Director	Nov 9 Form 4 ↗	Buy	+$100.0K 20,000 sh @ $5.00	+27.0%
David Pacitti Director	Nov 9 Form 4 ↗	Buy	+$100.0K 20,000 sh @ $5.00	+27.0%
David P. Hochman See Remarks, Director	Nov 9 Form 4 ↗	Buy	+$25.0K 5,000 sh @ $5.00	+27.0%
Andrew Lawrence Taylor Chief Financial Officer	Nov 9 Form 4 ↗	Buy	+$5,000 1,000 sh @ $5.00	+27.0%

All OBIO insider trades →Planned sales (Form 144): see notices

Insider trades

Open-market trades from Form 4. 10b5-1 marks a plan set in advance.

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13F holders

9.63M shares

56 funds report OBIO. Values checked against market prices.

Funds own 46% of shares (Q2 2026)

77 funds hold the stock.

Q3 2026: 12% · 5,560 of ~8,900 funds reported so far

Q2 202534%
Q3 202541%
Q4 202538%
Q1 202639%
Q2 202646%
Q3 2026 (so far)12%

Q3 2026. 16 new, 22 added to, 9 trimmed, 37 exited since Q2 2026.

Top 13F holders
#
1	BlackRock, Inc. 13F ↗	2.72M	$16.9M	+8.2%
2	Vanguard Capital Management LLC 13F ↗	2.00M	$12.5M	-1.0%
3	Geode Capital Management, LLC 13F ↗	1.00M	$6.2M	-0.4%
4	Propel Bio Management, LLC 13F ↗	896,701	$5.6M	unchanged
5	State Street Corp 13F ↗	605,778	$3.8M	+17.4%
6	UBS Group AG 13F ↗	525,068	$3.3M	+61.2%
7	Vanguard Fiduciary Trust Co 13F ↗	299,755	$1.9M	+2.6%
8	Vanguard Portfolio Management LLC 13F ↗	280,766	$1.7M	+2.1%
9	Knott David M Jr 13F ↗	253,651	$1.6M	unchanged
10	Simplify Asset Management Inc. 13F ↗	219,387	$1.4M	unchanged

Download CSV Every fund that holds OBIO, not only these ten. A download holds at most 10,000 rows; narrow the filters to get a smaller slice.

13F holders

Funds that report this stock, checked against market prices.

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Trades by members of Congress

Disclosed in dollar ranges, up to 45 days after the trade.

No recent congressional trades for this company.

Trades by members of Congress

Disclosed in dollar ranges, up to 45 days after the trade.

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Lobbying

What Orchestra BioMed Holdings, Inc. and its lobbying firms report each quarter.

No recent lobbying filings for this company.

Lobbying

What Orchestra BioMed Holdings, Inc. and its lobbying firms report each quarter.

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Institutional ownership over time

How many funds reported holding the stock at the end of each quarter, and how many shares they held between them.

Funds holding the stock

Shares they report

Funds holding the stock by quarter

Q4 2022	1	—	685,801	$6.9M
Q1 2023	22	+21	9.87M	$193.2M
Q2 2023	39	+17	10.79M	$75.5M
Q3 2023	42	+3	13.09M	$114.2M
Q4 2023	39	-3	13.31M	$121.5M
Q1 2024	43	+4	13.38M	$70.5M
Q2 2024	47	+4	14.23M	$116.0M
Q3 2024	48	+1	19.04M	$97.8M
Q4 2024	54	+6	19.25M	$77.0M
Q1 2025	56	+2	18.99M	$81.3M
Q2 2025	59	+3	18.14M	$47.6M
Q3 2025	52	-7	22.89M	$56.1M
Q4 2025	63	+11	21.70M	$90.1M
Q1 2026	65	+2	23.09M	$98.2M
Q2 2026	77	+12	27.69M	$119.4M
Q3 2026	56	-21	9.63M	$59.9M

Each point is a quarter-end, from Q4 2022 to Q3 2026. A fund's 13F lists its long positions in US-listed securities as of the last day of the quarter and arrives up to 45 days later, so each point shows holdings at quarter-end, not on the day they were reported.

Common shares only; options and bonds are left out. When a fund amends a report, the amended version is the one counted.

The history follows the company's current CUSIP number (68572M106). If the company's shares were ever re-issued under a different CUSIP, the quarters before the change are not part of this series, so the first point (Q4 2022) can be later than the stock's first appearance in 13F reports.

Share counts are adjusted for stock splits; none took place between these quarters. Values are in dollars as reported at the time and are not adjusted.

A quarter appears once our daily update has built its summary. If a summary cannot be built, older reports are kept and the chart shows the quarters it has until the next update repairs it.

Institutional ownership over time

How many funds reported holding the stock at the end of each quarter, and how many shares they held between them.

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More filings and data

Each opens the table.

Ownership stakes5 in 12 mo 8-K events3 in 90 days PatentsNone on record Short interestFINRA · updated Oct 15 Planned insider salesForm 144 · 6 in 12 mo Executive payNone on record Wikipedia attentionNone on record SEC enforcementNone on record Clinical trials2 active IPO history2 registrations Ownership stakes…8-K events…Patents…Short interest…Planned insider sales…Executive pay…Wikipedia attention…SEC enforcement…

About the company

The basics from the company’s SEC registration.

Legal name: Orchestra BioMed Holdings, Inc.
Address: 150 UNION SQUARE DRIVE, NEW HOPE, PA 18938
Phone: 646-343-9298
Fiscal year ends: Dec 31
Filer category: Non-accelerated filer, smaller reporting company
Incorporated in: DE
Listed as: OBIO (Nasdaq)
Former names: Health Sciences Acquisitions Corp 2 (until 2023)
SEC filings: All filings on SEC EDGAR ↗

About the company

The basics from the company’s SEC registration.

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$7.25+$1.10 (+17.89%) Nov 13 close

1M3M1Y

Oct 13, 2026Low $5.45 · High $7.25Nov 13, 2026

Aug 13, 2026Low $4.41 · High $7.25Nov 13, 2026

Nov 13, 2025Low $3.49 · High $7.25Nov 13, 2026

Congress purchase Congress sale Insider sale over $1M

Adjusted for stock splits; not for dividends. Where prices come from.

Live chart

Intraday and historical prices from TradingView. Quotes may be delayed.

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Information, not investment advice. Company matching is automatic; check the source before relying on one row.